Although your doctor is the best source for answering your specific questions about high cholesterol or high blood pressure and treatment with CADUET, you can find answers to common questions here.

To see questions, click on the topics below.


CADUET is 2 medicines in 1.

CADUET is a prescription drug that combines NORVASC® (amlodipine besylate) tablets for high blood pressure and LIPITOR® (atorvastatin calcium) tablets for high cholesterol—in 1 pill to significantly lower high blood pressure and high cholesterol.

The 2 main ingredients of CADUET have been proven to help lower high blood pressure and high LDL cholesterol along with diet and exercise.

CADUET is used in adults who need both NORVASC and LIPITOR.

NORVASC is used to treat:

  • High blood pressure (hypertension) and
  • Chest pain (angina) and
  • Blocked arteries of the heart (coronary artery disease)

LIPITOR is used to lower the levels of "bad" cholesterol and triglycerides in your blood. It can also raise the levels of "good" cholesterol.

LIPITOR is also used to lower the risk for heart attack, stroke, certain types of heart surgery, and chest pain in patients who have heart disease or risk factors for heart disease such as:

  • age, smoking, high blood pressure, low levels of "good" cholesterol, heart disease in the family

LIPITOR can lower the risk for heart attack or stroke in patients with diabetes and risk factors such as:

  • diabetic eye or kidney problems, smoking, or high blood pressure

LIPITOR has not been studied in people who have an increase of chylomicrons (Fredrickson Types I and V)

CADUET has not been studied in children.

CADUET is available by prescription only, so you’ll need to ask your doctor if CADUET is right for you.


Here are 3 suggested tips to help make sure you receive brand-name CADUET and not a generic:

  1. At your doctor’s office: Ask your doctor to prescribe brand-name CADUET and to indicate “DAW” (Dispense As Written)—or the language used in your state—on all of your CADUET prescriptions.
  2. At your pharmacy’s drop-off: Tell the pharmacist that you want brand-name CADUET—and be sure to use the CADUET Savings Card. The CADUET Savings Card can only be used with brand-name CADUET.
  3. At your pharmacy’s pick-up: Check your pills to be sure they’re brand-name CADUET—not the generic—and also check that you’ve saved on your prescription.

Image of pills in all available strengths

Talk to your doctor and/or your pharmacist to ask if you should be getting brand-name CADUET.

Check your pills for the distinctive shape and markings of brand-name CADUET.

Image of pills in all available strengths


The CADUET Savings Card allows eligible patients to pay as little as $4 every time they get a 30-day fill of brand-name CADUET—and could save up to $1,800 a year. If you have a prescription for brand-name CADUET, you can use the card for every fill through December 31, 2023.*

*Terms and conditions apply.

There are 2 ways to use the card immediately. Once you’ve activated your Savings Card, you can either:

  • Bring a printed copy of it to the pharmacy
  • Show it to your pharmacist on your phone

You can keep this card with you and continue to save on each fill for CADUET through December 31, 2023.

To be eligible to use a CADUET Savings Card:

  • You do not have insurance from any Federal Healthcare Program (including Medicare, Medicaid, Tricare, or any other state or federal medical pharmaceutical benefit program or pharmaceutical assistance program)
  • You and your spouse/partner are both not over age 65 and retired
  • You do not receive Social Security Disability Insurance (SSDI) or any other Social Security Administration (SSA) benefits
  • Neither you, your spouse or your parents are on active military duty and if so, you are not covered by their military health insurance
  • You do not have End-Stage Renal Disease (ESRD)
  • You are over the age of 18
  • You agree to the Terms and Conditions

To learn the full details of who is eligible, please see the full Terms and Conditions.

To get a Savings Card, register here and then download your card or have it sent to you via mail or email.

The CADUET Savings Card can only be used for new prescriptions that are filled after you have activated the card.

Yes, for reimbursement when using a nonparticipating pharmacy: Pay for your CADUET prescription, and mail a copy of the original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: Viatris, ATTN: CADUET, P.O. Box 6875, Bridgewater, NJ 08807.

Be sure to include a copy of the front of your CADUET Savings Card, your name, and mailing address.

Please expect up to 4 to 6 weeks for reimbursement.

Yes, for reimbursement when using the CADUET Savings Card through a mail-order pharmacy: Pay for your CADUET prescription, and mail a copy of the original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: Viatris, ATTN: CADUET, P.O. Box 6875, Bridgewater, NJ 08807.

Be sure to include a copy of the front of your CADUET Savings Card, your name, and mailing address.

Please expect up to 4 to 6 weeks for reimbursement.


  • Take CADUET once a day, exactly as your doctor tells you. Do not change your dose or stop CADUET without talking to your doctor.
  • Take CADUET each day at any time of day, at about the same time each day. CADUET can be taken with or without food.
  • Do not break the tablets before taking them. Talk to your doctor if you have a problem swallowing pills.
  • Your doctor should start you on a low-fat diet before giving you CADUET. Stay on this low-fat diet when you take CADUET.
  • If you miss a dose, take it as soon as you remember. Do not take CADUET if it has been more than 12 hours since your missed dose. Just take the next dose at your regular time. Do not take 2 doses of CADUET at the same time.
  • If too much CADUET is taken by accident, call your doctor or poison control center, or go to the nearest emergency room.

Tell your doctor about all of your health conditions, including, if you have:

  • heart disease
  • muscle aches or weakness
  • diabetes
  • thyroid problems
  • kidney problems
  • or drink more than 2 glasses of alcohol daily

Tell your doctor about all the medicines you take including prescription and nonprescription medicines, vitamins, and herbal supplements. CADUET and some other medicines can interact, causing serious side effects. Especially tell your doctor if you take medicines for:

  • your immune system
  • infections
  • cholesterol
  • birth control
  • heart failure
  • HIV (AIDS)

You can use nitroglycerin and CADUET together. If you take nitroglycerin for chest pain (angina), do not stop taking it while taking CADUET.

Know all the medicines you take. Keep a list of them with you to show your doctor and pharmacist.

  • Avoid getting pregnant. If you get pregnant, stop taking CADUET right away and call your doctor.
  • Do not breastfeed. CADUET can pass into your breast milk and may harm your baby.

  • Store CADUET at room temperature, 68 to 77°F (20 to 25°C).
  • Do not keep medicine that is out-of-date or that you no longer need.
  • Keep CADUET and all medicines out of the reach of children. Keep medicines in places where children cannot get it.


Do not use CADUET if you:

  • Are pregnant or think you may be pregnant, or are planning to become pregnant. CADUET may harm your unborn baby. If you get pregnant, stop taking CADUET and call your doctor right away.
  • Are breastfeeding. CADUET can pass into your breast milk and may harm your baby. Do not breastfeed if you take CADUET.
  • Have liver problems.
  • Are allergic to anything in CADUET. The active ingredients are atorvastatin calcium and amlodipine besylate.

See the Patient Product Information for a complete list of ingredients.

CADUET can cause serious side effects. These side effects happen only to a small number of people. Your doctor can monitor you for them. These side effects usually go away if your dose is lowered or CADUET is stopped. These serious side effects include:

  • Muscle problems. CADUET can cause serious muscle problems that can lead to kidney problems, including kidney failure. You have a higher chance for muscle problems if you are taking certain other medicines with CADUET
  • Liver problems. Your doctor should do blood tests to check your liver before you start taking CADUET and if you have symptoms of liver problems while you take CADUET. Call your doctor right away if you have the following symptoms of liver problems:
    • feel tired or weak
    • loss of appetite
    • upper belly pain
    • dark amber colored urine
    • yellowing of your skin or the whites of your eyes
  • Low blood pressure or dizziness
  • Muscle rigidity, tremor and/or abnormal muscle movement

Call your doctor right away if:

  • you have muscle problems like weakness, tenderness, or pain that happen without a good reason, especially if you also have a fever or feel more tired than usual. This may be an early sign of a rare muscle problem
  • muscle problems that do not go away even after your doctor has advised you to stop taking CADUET. Your doctor may do further tests to diagnose the cause of your muscle problems
  • allergic reactions including swelling of the face, lips, tongue, and/or throat that may cause difficulty in breathing or swallowing which may require treatment right away
  • you have nausea and vomiting, stomach pain
  • you are passing brown or dark-colored urine
  • you feel more tired than usual
  • your skin and white of your eyes get yellow
  • you have allergic skin reactions
  • Chest pain that does not go away or gets worse. Sometimes when you start CADUET or increase your dose, chest pain can get worse or a heart attack can happen. If this happens, call your doctor or go to the emergency room right away

Common side effects of CADUET include:

  • Diarrhea
  • Swelling of your legs or ankles
  • Nausea
  • Upset stomach
  • Muscle and joint pain
  • Alterations in some laboratory blood tests

Additional side effects have been reported: tiredness, tendon problems, memory loss, and confusion.

Talk to your doctor or pharmacist about side effects that bother you or do not go away.

There are other side effects of CADUET. Ask your doctor or pharmacist for a complete list.


High blood pressure is when the force of blood against the walls of the arteries stays high. This can damage the heart and other parts of the body. Drugs that lower blood pressure lower the risk of having a stroke or heart attack.

Angina is a pain that keeps coming back when part of the heart does not get enough blood. It feels like something is pressing or squeezing a person's chest under the breastbone. Sometimes it can be felt in shoulders, arms, neck, jaw, or back.

Cholesterol is a fat-like substance made in your body. It is also found in foods. You need some cholesterol for good health, but too much is not good for you. Cholesterol can clog your blood vessels.

A heart attack occurs when heart muscle does not get enough blood. Symptoms include chest pain, trouble breathing, nausea, and weakness. Heart muscle cells may be damaged or die. The heart cannot pump well or may stop beating.

A stroke occurs when nerve cells in the brain do not get enough blood. The cells may be damaged or die. The damaged cells may cause weakness or problems speaking or thinking.